Ongoing Clinical Trials (Not Recruiting)

Access our list of ongoing clinical trials (Not Recruiting)

Lung Cancer

Daiichi Sankyo DS1062-A-U303

A Randomized Phase 3 Study of Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab, with or Without Platinum Chemotherapy, in Subjects with No Prior Therapy for Advanced or Metastatic PD-L1 TPS <50% Non-squamous Non-small Cell Lung Cancer Without Actionable Genomic Alterations (TROPION-Lung07)

Study Link

Daiichi Sankyo DS1062-A-U304

A Randomized, Open-label, Phase 3 Trial of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in Treatment-naïve Subjects with Advanced or Metastatic PD-L1 High (TPS ≥50%) Non-small Cell Lung Cancer Without Actionable Genomic Alterations (TROPION-Lung08)

Study Link

MCLA-158-CL04

A Phase 2 Study to Investigate the Safety and Efficacy of Petosemtamab in Combination with Docetaxel as Second-Line Treatment in Adults with Metastatic Non-Small Cell Lung Cancer or in Combination with Pembrolizumab as First-Line Treatment

Study Link
Solid Tumour

Revolution Medicines RMC-6291-001

Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors

Study Link

Atridia SHR-A1904-I-104

An Open-label, Single-arm, Multi-center Phase I/IIa Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of SHR-A1904 in Subjects with Advanced Solid Tumours Expressing Claudin 18.2

Study Link

Seagen SGNDV-005

Phase 2 Basket Study of Disitamab Vedotin in Adult Subjects with Previously Treated, Locally Advanced Unresectable or Metastatic Solid Tumors that Express HER2

Study Link

Ascendis ASND0029

TransCon IL-2 β/γ Alone or in Combination with Pembrolizumab or Standard of Care Chemotherapy in Participants Aged 18 Years or Older with Locally Advanced or Metastatic Solid Tumor Malignancies

Study Link

Seagen SGNDV-004

A Phase 1b/2 Open-Label Study of Disitamab Vedotin Monotherapy or in Combination with Other Anticancer Therapies in Solid Tumors

Study Link
Prostate Cancer

USyd ENZAMET

Randomised Phase 3 Trial of Enzalutamide in First Line Androgen Deprivation Therapy for Metastatic Prostate Cancer: ENZAMET

Study Link
Breast Cancer

Daiichi Sankyo DS8201-A-U302

A Phase 3, Multicenter, Randomized, Open-Label, Active-Controlled Study of DS-8201a (Trastuzumab Deruxtecan) Versus Ado Trastuzumab Emtansine for HER2-Positive, Unresectable and/or Metastatic Breast Cancer

Study Link

Olema OP-1250-002

A Phase 1 Dose Escalation and Expansion Open-label, Multicenter Study of OP-1250 in Combination With the CDK4/6 Inhibitor Palbociclib in Adult Subjects With Advanced or Metastatic HR-positive, HER2-negative Breast Cancer

Study Link

Hoffmann-La Roche WO41554

A Phase III, Randomized, Double-Blind, Placebo-Controlled Study Evaluating Inavolisib Plus Palbociclib and Fulvestrant Versus Placebo Plus Palbociclib and Fulvestrant in Patients With PIK3CA-Mutant, Hormone Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer

Study Link

BioNTech BNT327-02

A Phase II, Multi-site, Randomized, Open-label Clinical Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of BNT327 at Two Dose Levels in Combination with Chemotherapeutic Agents as First- and Second-Line Treatment in Triple-Negative Breast Cancer

Study Link
Haematological Malignancies

Regeneron R1979-ONC-1625

An Open-Label Study to Assess the Anti-Tumor Activity and Safety of REGN1979, an Anti-CD20 X Anti-CD3 Bispecific Antibody, in Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Study Link

Ascentage APG-2575CU101

A Phase Ib/II Study of APG-2575 as a Single Agent or in Combination with Other Therapeutic Agents in Patients with Relapsed and/or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (SACRED)

Study Link
Bladder and Urothelial Cancer

Seagen RC48-G001

A Phase 2 Multi-Cohort, Open-Label, Multi-Center Clinical Study Evaluating the Efficacy and Safety of Disitamab Vedotin in Subjects with HER2-Expressing Locally Advanced Unresectable or Metastatic Urothelial Carcinoma

Study Link

Ractigen RAG-01-01

A Phase I, Open-label, Multi-center Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of RAG-01 in Patients with Non-muscle-invasive Bladder Cancer Who Have Failed Bacillus Calmette-Guérin Therapy

Study Link